I am getting the following behavior when using virtualenv to easy_install ZODB3. [ngift@Macintosh-7][H:10256][J:0]# virtualenv --no-site-packages zodbENV New python executable in zodbENV/bin/python Installing setuptools..........................done. [ngift@Macintosh-7][H:10257][J:0]# zodbENV/bin/easy_install ZODB3 Searching for ZODB3 Best match: ZODB3 3.8.0 Processing ZODB3-3.8.0-py2.5-macosx-10.5-i386.egg Adding ZODB3 3.8.0 to easy-install.pth file Installing mkzeoinst script to /Users/ngift/Documents/writing/IBM/ZODB/ zodbENV/bin Installing fstail script to /Users/ngift/Documents/writing/IBM/ZODB/ zodbENV/bin Installing zeopack script to /Users/ngift/Documents/writing/IBM/ZODB/ zodbENV/bin Installing runzeo script to /Users/ngift/Documents/writing/IBM/ZODB/ zodbENV/bin Installing zeopasswd script to /Users/ngift/Documents/writing/IBM/ZODB/ zodbENV/bin Installing zeoctl script to /Users/ngift/Documents/writing/IBM/ZODB/ zodbENV/bin Installing fsdump script to /Users/ngift/Documents/writing/IBM/ZODB/ zodbENV/bin Installing fsrefs script to /Users/ngift/Documents/writing/IBM/ZODB/ zodbENV/bin Installing repozo script to /Users/ngift/Documents/writing/IBM/ZODB/ zodbENV/bin Installing fsoids script to /Users/ngift/Documents/writing/IBM/ZODB/ zodbENV/bin Using /Library/Python/2.5/site-packages/ZODB3-3.8.0-py2.5-macosx-10.5- i386.egg Processing dependencies for ZODB3 Searching for zope.interface Reading http://pypi.python.org/simple/zope.interface/ Reading http://zope.org/Wikis/Interfaces/FrontPage Best match: zope.interface 3.4.1 Downloading http://pypi.python.org/packages/source/z/zope.interface/zope.interface-3.4.1... =b085f4a774adab688e037ad32fbbf08e Processing zope.interface-3.4.1.tar.gz Running zope.interface-3.4.1/setup.py -q bdist_egg --dist-dir /var/ folders/LZ/LZFo5h8JEW4Jzr+ydkXfI++++TI/-Tmp-/easy_install-2eJgo2/ zope.interface-3.4.1/egg-dist-tmp-qzXWo6 Adding zope.interface 3.4.1 to easy-install.pth file Installed /Users/ngift/Documents/writing/IBM/ZODB/zodbENV/lib/ python2.5/site-packages/zope.interface-3.4.1-py2.5-macosx-10.5-i386.egg Finished processing dependencies for ZODB3