just try  f2py according to http://www.scipy.org/F2PY_Windows.  The following  woks in dos  cmd window. E:\Miser3p2F\opcntrl\python E:\python25\scripts\f2py.py -c --fcompiler=gnu95 --compiler=mingw32 -lmsvcr71 -m cobyla cobyla.pyf cobyla2.f trstlp.f But I directly run run_compile() of  f2py2e with     sys.argv=sys.argv+['-c','--fcompiler=gnu95','--compiler=mingw32', '-lmsvcr71','-m', 'cobyla','E:\\Miser3p2F\opcntrl\\cobyla.pyf','E:\\Miser3p2F\opcntrl\\cobyla2.f','E:\\Miser3p2F\opcntrl\\trstlp.f'] , it does not work. I have tried several simple examples, they all work. I do not know why.   ghzhao from Curtin ___________________________________________________________ 好玩贺卡等你发，邮箱贺卡全新上线！ http://card.mail.cn.yahoo.com/