2012/6/13 Tobias Oberstein <tobias.oberstein@tavendo.de>
I am offering a 300 $ reward to anyone fixing

https://bugs.pypy.org/issue1162

We want to use Twisted on PyPy with OpenSSL on a network server involving threads, and above issue is blocking this.

Anyone?

Did you try with a recent nightly build? One created after this change:
http://mail.python.org/pipermail/pypy-commit/2012-June/063032.html 

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Amaury Forgeot d'Arc