I am not sure if CFFI list a better place to post about this one, but it seems to me that you may be interested in the initiative to create GCC that can link to MS VS runtimes. Probably it can be used to cross-compile right stubs for interoperability with C code on Windows platform. https://mingwpy.github.io/ https://groups.google.com/forum/#!topic/mingwpy/z6TMklH56w8 -- anatoly t.