"c" is an alternative to distutils' Extension() support or Makefile compilation of simple extension modules. It provides a meta_path hook that performs compilation and linkage of C, C++, or Objective-C source files upon import. Any Python implementation providing a functional "sysconfig" module should work. NOTE: Naturally, win32/win64 is not likely functional. Sorry. Currently, there is no way to build out compilation and link parameters, but future version are planned to include a cute solution to the problem. (Likely, embedding pkgconfig and -framework references in the C source requiring them) http://pypi.python.org/pypi/c