I have just released Shed Skin 0.6, an optimizing (restricted-)Python-to-C++ compiler. Most importantly, this release comes with a substantial scalability improvement. It should now be possible to compile programs into several thousands of lines, as shown by the new Commodore 64 emulator example (around 2000 lines, sloccount). Please see my blog for the full announcement:
Or go straight to the homepage:
Please have a look at the tutorial, try it out, and report issues at the homepage.