wxPython 2.2.2 has finally been released! You can get your copy at http://wxPython.org/download.php. At that site you'll find the sources, docs, and binaries for Linux and Win32 for both Python 1.5.2 and Python 2.0
Here's an excerpt from the CHANGES.txt file:
New in 2.2.2 ------------
Significantly changed how the wxStyledtextCtrl code that wraps Scintilla is implemented. Most of it is now automatically generated from an interface definition file provided by Scintilla. This means that it will be much easier to stay in sync with new Scintilla releases, but also means that some of the method and identifier names have changed. See wxPython/demo/data/stc.h for a copy of the C++ interface from which the Python interface is generated. There is now some inline documentation in that file that should really help explain how things work.
I am now using the Python Distutils to build wxPython and to make some of the distribution files. (See http://www.python.org/sigs/distutils-sig/) This means no more messing with my kludgy build.py/Makefile hack, builds will be more consistent with other Python extensions that also use Distutils, and will hopefully make wxPython easier to build for platforms where there have been troubles before. If you are building wxPython for Python 1.5.2 or for 1.6, then you will need to get and install version 1.0 of Distutils from the website above. If you are using Python 2.0 then you already have it.
Added wxInputStream and the wxFileSystem family of classes, contributed by Joerg Baumann.
Added wxProcess and support for it to wxExecute. wxProcess lets you get notified when an asyncronous child process terminates, and also to get input/output streams for the child process's stdout, stderr and stdin.
Removed the old python sizers.
Added __add__, __sub__ and __cmp__ (equality check only) for wxPoint and wxRealPoint.
Changed the build to make one big extension module instead of one for the core and each contrib. This allowed me to do away with the libwxPyHelpers.so on unix systems.
Lots of little fixes here and there.
Some hacks on wxGTK to try and make the AutoComplete listbox in the wxStyledTextCtrl to behave better. It's still not as nice as on wxMSW, but at least it's a bit more usable now.