Hello,
I was looking at the possibility of replacing the SEEK_* constants by IntEnums, and the first thing that catches attention is that these constants are defined in both Lib/os.py and Lib/io.py; both places also recently started supporting SEEK_HOLE and SEEK_DATA (though here io refers to os.SEEK_HOLE and os.SEEK_DATA).
Additional data points: other modules take these constants as arguments -
* mmap: directs to use os.SEEK_*
* chunk and fcntk: spell out the numeric values.