I just tried to build wxPython on x86_64 (athlon64) on Fedora core3 test 3. It didn't work. It looks like python is a 64-bit exec on this platform, and there is /usr/lib64/python2.3/ with what looks like the usual stuff. There is also a /usr/lib/python2.3, with not much in it, but I guess if you install a 32-bit python it would go there. Anyway, distutils/sysconfig.py def get_python_lib(... if os.name == "posix": libpython = os.path.join(prefix, "lib", "python" + get_python_version()) This is wrong, and it doesn't seem to give me anyway to overide the choice. Is there a fix?