Software Carpentry: GUI Toolkit?

Hi, folks. I'm putting together guidelines for submissions to the Software Carpentry design competition (www.software-carpentry.com), and would like to know what I should recommend as a Python GUI toolkit. As I understand it, the alternatives are:
- Tkinter: the "standard" answer, but many people think it's showing its age, and it's an installation and update headaches because of its Tcl dependencies.
- some other GUI toolkit: but there's no consensus on which one, and documentation is lacking.
- CGI scripts (i.e. all interfaces are web pages): has the virtue of simplicity, but could also make some useful interfaces difficult to build (e.g. no drag and drop), and would require users to run a server, or at least get exec privileges, which can be an installation headache.
If I've missed a good answer, or if there's somewhere else I should look for a solution, I'd be grateful for a pointer.
Thanks, Greg
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gvwilson@nevex.com