I thought I would share a recent use I had for "given": I have this comprehension: potential_updates = {y: command.create_potential_update(y) for x in need_initialization_nodes for y in [x, *x.synthetic_inputs()]} I want to filter out values that are None. I don't want to call the function call twice, so I have to resort to using a loop and appending or the for z in [y] trick. With "given", I can write: potential_updates = { y: potential_update for x in need_initialization_nodes for y in [x, *x.synthetic_inputs()] given potential_update = command.create_potential_update(y) if potential_update is not None} I also wanted to point out that code like this is self-commenting because the key and value of the comprehension can be given names.