Hi As you may have seen, AMD has recently announced CPUs that have much larger L3 caches. Does anyone know of any work that's been done to research or make critical Python code and data smaller so that more of it fits in the CPU cache? I'm particularly interested in measured benefits. This search https://www.google.com/search?q=python+performance+CPU+cache+size provides two relevant links https://www.oreilly.com/library/view/high-performance-python/9781449361747/c... https://www.dlr.de/sc/Portaldata/15/Resources/dokumente/pyhpc2016/slides/PyH... but not much else I found relevant. AnandTech writes about the chips with triple the L3 cache: https://www.anandtech.com/show/17323/amd-releases-milan-x-cpus-with-3d-vcach... "As with other chips that incorporate larger caches, the greatest benefits are going to be found in workloads that spill out of contemporary-sized caches, but will neatly fit into the larger cache." And also: https://www.anandtech.com/show/17313/ryzen-7-5800x3d-launches-april-20th-plu... " As detailed by the company back at CES 2022 and reiterated in today’s announcement, AMD has found that the chip is 15% faster at gaming than their Ryzen 9 5900X." I already know that using Non Uniform Memory Access (NUMA) raises the difficult problem of cache coherence. https://en.wikipedia.org/wiki/Non-uniform_memory_access https://en.wikipedia.org/wiki/Cache_coherence -- Jonathan