Following the discussion here (https://link.getmailspring.com/link/7D84D131-65B6-4EF7-9C43-51957F9DFAA9@getmailspring.com/0?redirect=https%3A%2F%2Fbugs.python.org%2Fissue36410&recipient=cHl0aG9uLWlkZWFzQHB5dGhvbi5vcmc%3D) I propose to add 3 new string methods: str.trim, str.ltrim, str.rtrim Another option would be to change API for str.split method to work correctly with sequences. In [1]: def ltrim(s, seq): ...: return s[len(seq):] if s.startswith(seq) else s ...: In [2]: def rtrim(s, seq): ...: return s[:-len(seq)] if s.endswith(seq) else s ...: In [3]: def trim(s, seq): ...: return ltrim(rtrim(s, seq), seq) ...: In [4]: s = 'mailto:maria@gmail.com' In [5]: ltrim(s, 'mailto:') Out[5]: 'maria@gmail.com' In [6]: rtrim(s, 'com') Out[6]: 'mailto:maria@gmail.' In [7]: trim(s, 'm') Out[7]: 'ailto:maria@gmail.co'