How is this not just a poorer version of PyPy's optimizations? If what you want is optimization, it would be much better to devote time to a solution that can potentially yield orders of magnitude worth of speedup like PyPy rather than increasing language complexity for a minor payoff.
I think he's already answered this twice between the two threads, plus at least once in the thread last year, not to mention similar questions from slightly different angles.
Which implies to me that the PEPs really need to anticipate and answer these questions.