With respect to Pythran:
Pythran is "for a subset of the Python language, with a focus on scientific computing." PysoniQ is not a subset of the Python language.
Currently Pythran is for Python 2.7 and "has decent Python 3 support." PysoniQ is Python 3.x only, and goes through the most recent release of CPython.
"Pythran depends on a few Python modules and several C++ libraries" which you will need to install manually. No installation is needed for PysoniQ.
Pythran also requires some code rewriting. PysoniQ does not.
With Pythran you also have to compile manually, but with PysoniQ that's not needed.
That's a very brief summary of some of the differences between PysoniQ and Cython, Nutika and Pythran.