AnyCPU assemblies can use x86 and x64 assemblies, as long as they run with corresponding architecture (check Prefer 32-bit setting if you are experiencing issue with x64 assembly).

You need a pythonnet dll matching your Python architecture.

Regards,

Victor

From: Govil Nag
Sent: Wednesday, March 4, 2020 1:51 AM
To: pythonnet@python.org
Subject: [Python.NET] DLL Processor compatibility

hallo,

pythonnet dll work either x64 bit processor or x86 processor ..is it possible to run it in visual Studio with "Any CPU"