I saw in scikit-image 14, add some snake method (chan_vese, morphological_chan_vese ...), It is very useful, but we need a good interactive enviroment to maxmize theirs advantage. So I integrate them into ImagePy, a plugin framework. Now It supports chan_vese, snake from bound, or snake from a roi. (If you like, it can save a gif animate).
Now ImagePy has integrated most function in scipy.ndimage and scikit-image. And It is esay to integrate any function based on Numpy ndarray.
Some snapshot in attachment.