Thank you all for your answers. finally I use OpenCV to perform the real-time computation and still use skimage for the initialisation on my real code.

I've joined a file that allows one to compare the computation we need to make.

There is a basic numpy method, the OpenCV one and the Skimage regionprops one. I don't find relevant to include a naive python implementation.

Please note that the values computed for visualization are for illustration only and doesn't represent a real experiment.

I Hope it can help to benchmark the future improvement of regionprops.

Best regards