<https://lh5.googleusercontent.com/-HJwNDOP7D1U/VP7KITX1mFI/AAAAAAAACXQ/zn1PhAafDCs/s1600/RCA_segmented.tif> Hi there, First of all, many thanks for this very nice and useful package! I just started using the skimage library and I do some image processing in very noisy angiographic data. After some image enhancement in the obtained images, I applied a canny edge detection algorithm implemented in skimage and I came up with the attached image (after dilation and erosion). Do you have any advice on how could I extract only the vessel edges automatically from the image? I looked in examples with labels or binary hole filling but it does not work well for my problem. Many thanks in advance, Giorgos