A postdoc position for an image analysis specialist is available at the Department of Molecular Structural Biology <http://www.biochem.mpg.de/en/rd/baumeister> at the Max Planck Institute (MPI) of Biochemistry (Martinsried, Germany). The project aims to develop data processing and segmentation techniques to analyze the structures found in cryo-electron tomograms of cells containing toxic protein aggregates in the context of neurodegenerative disease. The position can be funded for up to 5 years by an ERC Synergy Grant awarded to the ToPAG (Toxic Protein AGgregation in neurodegeneration) consortium formed by four MPI-Martinsried departments. The goal of this multidisciplinary initiative is to investigate the mechanisms by which protein misfolding leads to neurodegeneration in diseases such as Alzheimer’s or Parkinson’s. The MPI of Biochemistry hosts a world-class cryo-electron microscopy center with multiple high end transmission electron microscopes (including Titan Krios, Tecnai Polara, Tecnai F20), several of which are equipped with energy filters, direct electron detectors and phase plates. The Institute also houses advanced equipment for sample preparation and ample computational resources. Applicants should hold a Ph.D. degree in Computer Science or related disciplines and experience in 3D data processing, preferably cryo-electron tomography. To apply, please send a motivation letter, CV and contact information of two referees to Wolfgang Baumeister (baumeist@biochem.mpg.de) or Rubén Fernández-Busnadiego (ruben@biochem.mpg.de). Ruben Fernandez-Busnadiego, Ph. D. Project Group Leader Max Planck Institute of Biochemistry Dept. Molecular Structural Biology Am Klopferspitz 18 82152 Martinsried Germany