Hi, I compared skimage.io on an other ubuntu box (10.10), with readmagick//mahotas for 8 bits and 12 bits images. The script and the image are joined. As you can see, displaying a 16 bits image yield a saturated image and the orientation is mirrored. When a 8 bit png image is loaded the three libs (sio, readmagick mahotas), no difference can be seen. Should I use a github version to fix that issue? Thanks JP