Joseph, Ralf, Thank you both for your responses! I'm still very much new and unfamiliar with Python and it's libraries, so I appreciate your quick and courteous replies. The BytesIO library was exactly what I needed. I was able to load the WAV byte array data into scipy using that as a wrapper. If it's of any interest, my code roughly looked like this: ``` import boto3 import scipy.io.wavfile as sciwav from io import BytesIO s3 = boto3.resource('s3') #access bucket, get WAV data (i.e., b'RIFF\x86x.\x01WAVEfmt ...') object = s3.Object(bucket_name, key) result = object.get()['Body'].read() # wrap data and submit wrapper = BytesIO(result) wav_file = sciwav.read(wrapper) ``` I will also go back and review the documentation regarding using file-like objects and can add those details. Thank you again, Miles