I have CentOS release 5.6 (Final) I have defined the variables ATLAS=/usr/local/lib/libsatlas.so:/usr/local/lib/libtatlas.so BLAS=/usr/lib64/libblas.so LAPACK= FLAPACK=/usr/lib/liblapack.so.3 Executed the line to build and install scipy-0.11.0b1]# python setup.py install This ends with File "/usr/lib64/python2.4/site-packages/numpy/distutils/system_info.py", line 321, in get_info return cl().get_info(notfound_action) File "/usr/lib64/python2.4/site-packages/numpy/distutils/system_info.py", line 472, in get_info raise self.notfounderror(self.notfounderror.__doc__) numpy.distutils.system_info.LapackNotFoundError: Lapack (http://www.netlib.org/lapack/) libraries not found. Directories to search for the libraries can be specified in the numpy/distutils/site.cfg file (section [lapack]) or by setting the LAPACK environment variable. I have also tried LAPACK=/usr/lib/liblapack.so.3 How do I fix this problem? Atlas was built with ./configure --shared --prefix=/share/apps --with-netlib-lapack-tarfile=/share/apps/lapack-3.4.1.tgz