I'm totally confounded on this one. For some reason, when using twistd, web2 cannot be found by the interpreter. (I'm running Twisted SVN HEAD on pythonmac's Python 2.4 on Mac OS X.) For example, I've got the following code in a file called twisted.py from twisted.web2 import server, channel, static, wsgi def handler(env, start_response): pass # This part gets run when you run this file via: "twistd -noy modu/web/twisted.py" root = wsgi.WSGIResource(handler) site = server.Site(root) # Start up the server from twisted.application import service, strports application = service.Application("web2") s = strports.service('tcp:8888', channel.HTTPFactory(site)) s.setServiceParent(application) When running it (with twistd -noy twisted.py), I get: Traceback (most recent call last): File "/Library/Frameworks/Python.framework/Versions/Current/ bin/twistd", line 20, in ? from twisted.scripts.twistd import run File "/Users/phil/Desktop/twisted.py", line 1, in ? from twisted.web2 import server, channel, static, wsgi ImportError: No module named web2 This is a standard Twisted installation using `python setup.py install`, and web2 is clearly in my site-packages directory: optimus:~ phil$ ls -la /Library/Frameworks/Python.framework/ Versions/2.4/lib/python2.4/site-packages/twisted/web2 total 1272 drwxr-xr-x 54 root admin 1836 Jul 24 10:54 . drwxr-xr-x 36 root admin 1224 Jul 24 10:54 .. -rw-r--r-- 1 root admin 254 Jun 29 2006 __init__.py -rw-r--r-- 1 root admin 371 Jul 24 10:54 __init__.pyc ... ... Even stranger is that twistd doesn't seem to have any problems finding/loading the web2 plugin optimus:~ phil$ twistd Usage: twistd [options] ... ... ... Commands: web2 An HTTP/1.1 web server that can serve from a filesystem or application resource. ... ... ... And when running the exact interpreter path specified in twistd, there are no problems either: optimus:~ phil$ which twistd /Library/Frameworks/Python.framework/Versions/Current/bin/twistd optimus:~ phil$ head -n 1 /Library/Frameworks/Python.framework/ Versions/Current/bin/twistd #!/Library/Frameworks/Python.framework/Versions/2.4/Resources/ Python.app/Contents/MacOS/Python optimus:~ phil$ /Library/Frameworks/Python.framework/Versions/ 2.4/Resources/Python.app/Contents/MacOS/Python Python 2.4.3 (#1, Apr 7 2006, 10:54:33) [GCC 4.0.1 (Apple Computer, Inc. build 5250)] on darwin Type "help", "copyright", "credits" or "license" for more information. >>> from twisted.web2 import server >>> I had this same issue on my other development machine, also a Mac, but I assumed it was some kind of configuration issue with that machine in particular. Has anyone had a similar experience? Any help in this matter would be appreciated. -phil