Hi all, just installed the last wx and twisted and tring my already working app and: Traceback (most recent call last): File "threading.py", line 442, in __bootstrap self.run() File "threading.py", line 422, in run self.__target(*self.__args, **self.__kwargs) File "/usr/lib/python2.4/site-packages/twisted/internet/_threadedselect.py", line 149, in _workerInThread fn(*args) --- <exception caught here> --- File "/usr/lib/python2.4/site-packages/twisted/internet/_threadedselect.py", line 169, in _doSelectInThread [], timeout) exceptions.ValueError: file descriptor cannot be a negative integer (-1) and on shutdown: Traceback (most recent call last): File "/usr/lib/python2.4/site-packages/wx-2.8-gtk2-unicode/wx/_core.py", line 14364, in <lambda> lambda event: event.callable(*event.args, **event.kw) ) File "/usr/lib/python2.4/site-packages/twisted/internet/_threadedselect.py", line 243, in _interleave msg, args = self.toMainThread.get_nowait() File "/usr/lib/python2.4/Queue.py", line 141, in get_nowait return self.get(False) File "/usr/lib/python2.4/Queue.py", line 116, in get raise Empty Queue.Empty How debug it? Debian etch, python 2.4.4, wx 2.8.7.1, twisted 2.5.0 Thanks, Michele