On Feb 9, 2016, at 5:16 AM, Eric P. Mangold <teratorn@gmail.com> wrote:

Are you aware of anyone trying to use Twisted with PyOpenSSL/LibreSSL ? Just curious.

I am not aware of anyone using it with Twisted, but Cryptography does test with LibreSSL: https://jenkins.cryptography.io/job/cryptography-pr-builder/4964/ - so if you built your own wheel it ought to work.