[Neuroimaging] Affine transformations

[Stefan Hoffmann]

Dear all,

I'm training Neural Networks for Image Registration of T1/T2 images  
for my master thesis. I'm using the nibabel transformation functions to:

Scale, Rotate, Shift

batches of my MRI scans using homogeneous coordinates. Therefore I  
need to rotate and scale around the center of the cropped parts of the  
scans, while also shifting them.

Is there a smart way doing so?

I'd be so grateful for response.

Best regards,
Stefan