Problem running python program?

[Timothy Reaves]

	When I run a couple different programs, the following is what happens. 
Do I have python setup incorrectly?  Thanks.

[treaves at double treaves]$ export PYTHONHOME=/usr/lib/python2.1/
[treaves at double treaves]$ gnucash
Could not find platform independent libraries <prefix>
Could not find platform dependent libraries <exec_prefix>
Consider setting $PYTHONHOME to <prefix>[:<exec_prefix>]
'import exceptions' failed; use -v for traceback
Warning!  Falling back to string-based exceptions
'import site' failed; use -v for traceback
Fatal Python error: couldn't import os
Aborted (core dumped)
[treaves at double treaves]$ glimmer
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Could not find platform independent libraries <prefix>
Could not find platform dependent libraries <exec_prefix>
Consider setting $PYTHONHOME to <prefix>[:<exec_prefix>]
'import exceptions' failed; use -v for traceback
Warning!  Falling back to string-based exceptions
'import site' failed; use -v for traceback
Fatal Python error: could not import _gtk
Aborted (core dumped)