Pythonwin default directory init

[Costas Menico]

I use Pythonwin and I would like it if the File/Open or File/Save
would default to a directory of my choice when I start it up.

I have tried making a startup module to set the paths of sys but that
doesn't seem to work. I have looked thru the .py files trying to
figure out where I could fix this and can't find it.

Also setting it up as a shortcut on the Desktop defaults to the
Desktop. 

Does anyone know how to do this? 

TIA

Costas