Python GUI toolkit

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what would be the best python GUI toolkit, it must be cross platform.

i have tried gtk, but it interface are real bad and its coding was difficult
so i dropped it,

the only remaining are qt4 and wx, i would like to know if one of these or
any other toolkit is capable of creating good-looking GUI's, like in other
apps, for e.g, .net apps.

i m a noob, and willing to learn, so difficulty is no problem