html ui + py background? any tut?

[oyster]

I have read for many times that the modern appliaction (not a web one,
but desktop on) uses html + js for its UI, and python code is for the
background work
but I have never found event a simple (yet completed) article on how
to develop such a thing from scrach in these advocacy thing.

Can anyone point out some simple, can-be-followed tutorial on such
thing especially for windows os?

thanx