can I package a distutil based python app in deb?

[hackingKK]

Hello all,
I guess the subject line says it all.
I want to package a python app to deb.
I have 3 interesting issues with it.
1, I would want it to run on Ubuntu 10.04, Ubuntu 10.10, Ubuntu 11.04 
and Debian 5.
2, the package depends on another python package which is also distutil 
based.
3, The second package needs to run in a virtual environment.
This means that I not only have to figure out the dependencies but also 
have the deb to include a script to get the virtual environment script, 
then create one for the package, then download all dependencies (Pylons 
0.9.7 in this case along with report lab) and finally put the package 
into this virtual environment.
Is this all possible?
Happy hacking.
Krishnakant.