[Tutor] Creating a graphical interface to database of gene coordinates
Liam Clarke
ml.cyresse at gmail.com
Sat Apr 22 00:58:00 CEST 2006
For graphing you can't really beat Scipy.
On 4/22/06, Srinivas Iyyer <srini_iyyer_bio at yahoo.com> wrote:
> Dear group,
> I am happy that I am slowly finding pyhonian projects
> related to my research area.
>
> Problem:
> 1. I have a database of human gene coordinates on
> chromosomes.
> 2. I have gene expression data from my lab concerning
> the genes I mentioned above.
>
> 3. I want to visualize expression data laid on
> chromosomes.
>
> Eg.
> Coordinates:
> Chr Gene From To Exon
> 1 x 100 120 exon:1
> 1 x 200 250 exon:2
> 1 x 350 450 exon:3
>
>
> Expression data:
>
> IDent sample Chr From To Expression
> value
> xxx_at lung 1 110 120 100.35
> x_s_at heart 1 225 250 124.35
> x_a_at eye 1 375 400 146.35
>
> What I want:
>
> I want to have a simpler window, that would connect to
> my database. I want to give a gene, this python/tk
> interfacce or what ever would query the database
> draw a graph of gene according the exons and plot the
> values.
>
> -------_______----------_______-------
>
> -- : exon
> __: regions that are not exons, introns.
>
>
>
> My questions to Tutor/BioPython forums:
>
> 1. What should I decide to work on a. Py/Tk framework
> b. python imaging libraries etc.
>
> 2. I do not want to impress any one with this work,
> except that it should help me understand the
> relationships as the number game in the tables above
> is highly confusing. So, a working version that
> accurately plots the expression values for as many
> samples I have
>
> 3. Are there any available modules to jump-start? or
> do I have to create some from scratch. which would be
> a problem because I am between novice to mediocral
> level of python programing.
>
> 4. Any ideas/suggestions/pointers are highly
> appreciated.
>
> thanks
> Sri
>
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