Hello all, After following some examples around the web, and some discussions in the mail list, I came into the following snippet to call a function defined in a Python script into a C# host app, as seen at “http://mail.python.org/pipermail/pythondotnet/2007-June/000620.html”: // public static void MethodThatCallsPython() { // have to acquire the GIL to safely call back into Python!! IntPtr state = PythonEngine.AcquireLock(); PythonEngine.RunSimpleString("print 'hello'"); // done using python for now, so release the GIL... PythonEngine.ReleaseLock(state); } // Although it looks quite simple, VS2010 this throws an exception at the very first line of code: “Attempted to read or write protected memory. This is often an indication that other memory is corrupt.” My machine runs Windows 7 64-bit, and as I read somewhere else, 64 bit OS may be a matter of concern. Does anyone know how to overcome this annoying situation?? Thank you for any help provided! Igor Fier Dept. of Physics, Condensed Matter UNESP Rio Claro – Rio Claro-SP, Brazil