[Twisted-web] Application variables?

I'm new to using twisted.web. I come from a ColdFusion environment. I'm using rpy files that import and reload modules with resources that use the render method to send my content back to the client browser. I've successfully used Session to maintain session state for individual browsers. How does one share "application data" between requested scripts (or should I say resources)? That is, where do I declare and access variables to hold information that is to be shared by all requests? Do I use application or factory or the resource? Sorry if I'm using the wrong terminology to express these notions. Thank you for any assistance. Robert Rilee