We recently switched from these versions and recently our TLS health check using treq seems to be using more and more file handles and getting this exception. Additionally our health check gets response time outs at a much higher frequency. Any tips on how I would go about debugging this? Or is this perhaps a known issue in one of the versions below and I need to either bump up or down a release version? Thanks! twisted 16.6.0 -> 19.19.0 treq 15.1.0 -> 18.6.0 File "/home/foo/foo/local/lib/python2.7/site-packages/twisted/internet/epollreactor.py", line 183, in removeWriter EPOLLOUT, EPOLLIN) File "/home/foo/foo/local/lib/python2.7/site-packages/twisted/internet/epollreactor.py", line 160, in _remove self._poller.unregister(fd) exceptions.IOError: [Errno 2] No such file or directory